I began my internship with Dr. Miki’s lab at USC on Tuesday, June 3rd. Upon arrival, I discussed with Dr. Miki his plans for my stay as a member of his research team. Dr. Miki’s project, in an overarching sense, looks into the use of stem cell research to find a viable, more efficient, and more effective treatment for metabolic congenital liver diseases. My main project for the duration of the eight weeks is to prepare and run an array of a small molecule that has recently proven to have a positive effect on cancer: it seeks only the cancerous cells, and does not harm those that are healthy. The goal of the array is to observe the specific effect of this protein on certain antibodies, which could lead to insight on how it functions in vivo. I am to cultivate ES cells (called H9 cells) until they are confluent (the population has grown to the point of covering the entirety of the cell culture plate), induce differentiation into definitive endoderm cells, and extract the protein created by these cells to use in the array. I am also to extract RNA and sequence it in the hopes of learning more about the nature of this protein.